Products for Research Use Only

Bazedoxifene

CAT: 1568-C03679Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C03679Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
198481-32-2
Synonyms
TSE-424
SKU
C03679-5mg
Target
Estrogen/progestogen Receptor
Applications
Endocrinology & Hormones
Additionnal Information
Bazedoxifene (TSE-424) is a selective estrogen receptor modulator that binds to and activates ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. It also inhibits IL-6/GP130 interactions, suppresses STAT3 signaling, induces apoptosis, and reduces tumor growth, viability, and colony formation in cancer models, while being studied for effects on bone density, uterine health, and CNS vasomotor responses.