Pentamidine

CAT: 1568-C03414Size: 50 mgDry Ice: NoHazardous: No
CAT#:1568-C03414Size:50 mg
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CAS Number
100-33-4
Synonyms
MP-601205
SKU
C03414-50mg
Target
TLR
Applications
Immunology & Inflammation
Additionnal Information
Pentamidine (MP-601205) is an aromatic diamidine drug, an antagonist of TLR4.It also inhibits PI3K/AKT signaling pathway and reduce the expression of MMP-2 and MMP-9. It exhibits anti- protozoal, anti-inflammatory, and anti-tumor activities and is used as an agent for treating African trypanosomiasis, antimony resistant leishmaniasis and Pneumocystis carinii pneumonia.

100-33-4

PubChem
cas100-33-4
modify2026-05-17
descriptionPentamidine is a diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. It has a role as a calmodulin antagonist, a S100 calcium-binding protein B inhibitor, a xenobiotic, an antifungal agent, a trypanocidal drug, a NMDA receptor antagonist, a chemokine receptor 5 antagonist, an anti-inflammatory agent and an EC 2.3.1.48 (histone acetyltransferase) inhibitor. It is a carboxamidine, an aromatic ether and a diether. It is a conjugate base of a pentamidinium(2+).
synonyms
pentamidine100-33-4Pentamidina4,4'-(Pentamethylenedioxy)dibenzamidinePentamidinPentamidinum4,4'-Diamidinodiphenoxypentanep,p'-(Pentamethylenedioxy)dibenzamidinePentam 300 (as isethionate)Nebupent (as isethionate)+ 15 more
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Alternative Products

CatalogName
527056Pentamidine
TRC-P272515-250MGPentamidine Diamidoxime
TRC-P272501-1GPentamidine Diisethionate
sc-477687Pentamidine Amidoxime
BUP13318-01Pentamidine dihydrochloride
318465Pentamidine Isethionate
HY-B0537R-01Pentamidine (Standard)
HY-B0537CPentamidine (dimesylate)
MF-0141713-01Pentamidine dimesylate
TRC-P272502-25MGPentamidine-d10

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