Products for Research Use Only

Buloxibutid

CAT: 1568-C03231-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C03231-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
477775-14-7
Synonyms
AT2 Agonist C21
SKU
C03231-5mg
Target
Angiotensin Receptor
Applications
GPCR & G Protein
Additionnal Information
Buloxibutid (AT2 Agonist C21) is a selective agonist of angiotensin II type 2 receptor (AT2R) with a Ki value of 0.4 nM for the AT2 receptor and a Ki >10 μM for the AT1 receptor. Its treatment significantly reduces vascular remodelling, improves hemodynamics, and decreases pulmonary collagen deposition in the Sugen-Hypoxia model of pulmonary hypertension.