EGFR T790M/L858R-IN-4

• UNSPSC Description:

  EGFR T790M/L858R-IN-4 (Example 14) is a potent EGFRT790M/L858R inhibitor with anticancer effects[1].

• Target Antigen:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/egfr-t790m-l858r-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC(NC2=NC(N3C=CC4=CC=CN=C43)=CC=N2)=C(OC)C=C1C)/C=C/CN(C)C

• Molecular Weight:

  457.53

• References & Citations:

  [1]Guoqing Paul Chen, et al. Novel pyrimidine compound as kinase inhibitors with biological activities on egfr mutants. WO2024064091A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3032760-34-9