EGFR T790M/L858R-IN-4

EGFR T790M/L858R-IN-4

• CAS Number: 3032760-34-9
• UNSPSC Description: EGFR T790M/L858R-IN-4 (Example 14) is a potent EGFRT790M/L858R inhibitor with anticancer effects[1].
• Target Antigen: EGFR
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/egfr-t790m-l858r-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC(NC2=NC(N3C=CC4=CC=CN=C43)=CC=N2)=C(OC)C=C1C)/C=C/CN(C)C
• Molecular Weight: 457.53
• References & Citations: [1]Guoqing Paul Chen, et al. Novel pyrimidine compound as kinase inhibitors with biological activities on egfr mutants. WO2024064091A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported