JNJ-10198409

• CAS Number :

  627518-40-5

• SKU :

  C02074-5mg

• Target :

  PDGFR

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  COC1=CC2=C (C=C1OC) C3=C (C2) C (=N[NH]3) NC4=CC=CC (=C4) F

• Additionnal Information :

  JNJ-10198409, a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor with IC50 of 2 nM, is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent, has good activity against PDGFRβ kinase and PDGFRα kinase with IC50 of 4.2 and 45 nM, respectively.

• Storage Conditions :

  3 years -20°C powder