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Irpagratinib

CAT: 1568-C01995-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:1568-C01995-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230974-62-4
Synonyms
ABSK011
SKU
C01995-1mg
Target
FGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Irpagratinib (ABSK011) is a potent inhibitor of FGFR4 with an IC50 of < 10 nM in biochemical assays. It effectively suppresses FGFR4 auto-phosphorylation and disrupts downstream signal transduction. It also strongly inhibits tumor growth and induces regression in subcutaneous xenograft models.

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