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Lometrexol

CAT: 1568-C01857Size: 1 mgDry Ice: YesHazardous: No
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CAT#:1568-C01857Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
106400-81-1
Synonyms
DDATHF
SKU
C01857-1mg
Additionnal Information
Lometrexol (DDATHF), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent

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