AMG-193

• CAS Number :

  2790567-82-5

• SKU :

  C01756-5mg

• Target :

  PRMT

• Applications :

  Epigenetics

• Additionnal Information :

  AMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 μM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.