AMG-193

CAT: 1568-C01756-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C01756-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2790567-82-5
SKU
C01756-5mg
Target
PRMT
Applications
Epigenetics
Additionnal Information
AMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 μM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.

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