AU-15330

CAT: 1568-C01476-02Size: 10 mM / 1 mLDry Ice: NoHazardous: No

1 / 1

CAT#:1568-C01476-02Size:10 mM / 1 mL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2380274-50-8

SKU

C01476-5mg

Target

PROTAC

Applications

Others

Smiles

CC (NC (=O) C1CC (O) CN1C (=O) C (NC (=O) CN2CCN (CC2) C3=C (N) N=NC (=C3) C4=C (O) C=CC=C4) C (C) (C) C) C5=CC=C (C=C5) C6=C (C) N=CS6

Additionnal Information

AU-15330 is a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 and SMARCA4, which can induce potent inhibition of tumor growth in xenograft models of prostate cancer.

Storage Conditions

3 years -20°C powder

Chemical Information

(2S,4R)-1-((S)-2-(2-(4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

CAS Number	2380274-50-8
PubChem CID	156168451
IUPAC Name	(2S,4R)-1-[(2S)-2-[[2-[4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
Molecular Formula	C39H49N9O5S
Molecular Weight	755.9
XLogP	3.3
Topological Polar Surface Area	218
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	11
Heavy Atom Count	54
Formal Charge	0
Complexity	1280

SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CN4CCN(CC4)C5=CC(=NN=C5N)C6=CC=CC=C6O)O

InChI

InChI=1S/C39H49N9O5S/c1-23(25-10-12-26(13-11-25)34-24(2)41-22-54-34)42-37(52)31-18-27(49)20-48(31)38(53)35(39(3,4)5)43-33(51)21-46-14-16-47(17-15-46)30-19-29(44-45-36(30)40)28-8-6-7-9-32(28)50/h6-13,19,22-23,27,31,35,49-50H,14-18,20-21H2,1-5H3,(H2,40,45)(H,42,52)(H,43,51)/t23-,27+,31-,35+/m0/s1

InChIKey

HDCCMCFIGHIDJR-TUDDPRDOSA-N

Chemical Structure

2D Structure

CAS: 2380274-50-8

CID: 156168451

Formula: C39H49N9O5S

MW: 755.9

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	755.9
XLogP3	3.3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	11
Exact Mass	755.35773687
Monoisotopic Mass	755.35773687
Topological Polar Surface Area	218 Å²
Heavy Atom Count	54
Formal Charge	0
Complexity	1280
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BA4657-5	AU-15330
A23921-100	AU-15330 100mg
A23921-50	AU-15330 50mg
A23921-10	AU-15330 10mg
A23921-5	AU-15330 5mg
HE186005-2K	Au-PEG-NH2 (Au:15nm), 2K
HY-165489	AU-006
ABC-TC0056	AU-565
MBS5812346	AU-461
MBS5768246	AU-224

AU-15330

Chemical Information

Alternative Products

Popular Products