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YS-49

CAT: 1568-C01362-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C01362-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
132836-42-1
SKU
C01362-5mg
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
Br.OC1=CC2=C (C=C1O) C (CC3=C4C=CC=CC4=CC=C3) NCC2
Additionnal Information
YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells, inhibits angiotensin II (Ang II) -stimulated proliferation of VSMCs via induction of heme oxygenase (HO) -1, also is an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors.
Storage Conditions
3 years -20°C powder

Chemical Information

YS-49

structure given in first source

CAS Number132836-42-1
PubChem CID10249534
IUPAC Name1-(naphthalen-1-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrobromide
Molecular FormulaC20H20BrNO2
Molecular Weight386.3
Topological Polar Surface Area52.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity401
SMILES
C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=CC4=CC=CC=C43.Br
InChI
InChI=1S/C20H19NO2.BrH/c22-19-11-15-8-9-21-18(17(15)12-20(19)23)10-14-6-3-5-13-4-1-2-7-16(13)14;/h1-7,11-12,18,21-23H,8-10H2;1H
InChIKey
JXFRKNGQHAAJKY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of YS-49
CAS: 132836-42-1
CID: 10249534
Formula: C20H20BrNO2
MW: 386.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight386.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass385.06774
Monoisotopic Mass385.06774
Topological Polar Surface Area52.5 Ų
Heavy Atom Count24
Formal Charge0
Complexity401
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GTR19175615-01YS-49
T75238-01YS-49 monohydrate
HY-15477A-01YS-49 (monohydrate)
A21198-500YS-49 500mg
A21198-100YS-49 100mg
A21198-10YS-49 10mg
A21198-2YS-49 2mg
A21198-5YS-49 5mg
A21198-1YS-49 1mg
A21198-50YS-49 50mg

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