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CNQX

CAT: 1568-C01268-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C01268-01Size:5 mg
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CAS Number
115066-14-3
Synonyms
6-cyano-7-nitroquinoxaline-2,3-dione
SKU
C01268-5mg
Target
GluR
Applications
Neuronal Signaling
Smiles
[O-][N+] (=O) C1=CC2=C (NC (=O) C (=O) N2) C=C1C#N
Additionnal Information
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) is an AMPA and kainate receptor antagonist with IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively. CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM) . CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.
Storage Conditions
3 years -20°C powder

Chemical Information

6-Cyano-7-nitroquinoxaline-2,3-dione

6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.

CAS Number115066-14-3
PubChem CID3721046
IUPAC Name7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
Molecular FormulaC9H4N4O4
Molecular Weight232.15
XLogP0
Topological Polar Surface Area128
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Heavy Atom Count17
Formal Charge0
Complexity434
SMILES
C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N
InChI
InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
InChIKey
RPXVIAFEQBNEAX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-Cyano-7-nitroquinoxaline-2,3-dione
CAS: 115066-14-3
CID: 3721046
Formula: C9H4N4O4
MW: 232.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight232.15
XLogP30
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass232.02325462
Monoisotopic Mass232.02325462
Topological Polar Surface Area128 Ų
Heavy Atom Count17
Formal Charge0
Complexity434
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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