MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH

CAT:

804-HY-W731085

Size:

1 mg

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CAS Number: 2626930-84-3
UNSPSC Description: MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form an ADC-related drug-linker conjugate (Drug- Linker Conjugates for ADC).MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs)[1].
Target Antigen: ADC Linker
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/mc-ggfg-nh-ch2-o-ch2-s-cyclopropane-cooh.html
Purity: 98.48
Solubility: 10 mM in DMSO
Smiles: O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(O)=O)=O)=O)=O)=O)=O
Molecular Weight: 656.68
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
Clinical Information: No Development Reported

Cat	Name
HY-49929	MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH
HY-W731085	MC-GGFG-NH-CH2-O-CH2-(s-cyclopropane)-COOH
HY-400677	NH2-PEG4-GGFG-NH-CH2-O-CH2COOH
HY-131717-02	Thalidomide-NH-CH2-COOH
HY-131717-01	Thalidomide-NH-CH2-COOH
HY-400676	NH2-PEG4-GGFG-CH2-O-CH2-Cbz
HY-156810	Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz
HY-160453	MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH
HY-157813-02	2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
HY-157813-01	2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan