Products for Research Use Only
RegisterLogin

Enasidenib 25mg

CAT: 0628-A15808-25Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0628-A15808-25Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1446502-11-9

Chemical Information

Enasidenib

Enasidenib is a 1,3,5-triazine which is substituted by (2-hydroxy-2-methylpropyl)nitrilo, 6-(trifluoromethyl)pyridin-2-yl and [2-(trifluoromethyl)pyridin-4-yl]nitrilo groups at positions 2,4 and 6, respectively. It is an isocitrate dehydrogenase-2 (IDH2) inhibitor which has been approved for the treatment of adults with relapsed or refractory acute myeloid leukaemia (AML). It has a role as an EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor and an antineoplastic agent. It is a member of 1,3,5-triazines, a tertiary alcohol, an aromatic amine, an organofluorine compound, an aminopyridine and a secondary amino compound.

CAS Number1446502-11-9
PubChem CID89683805
IUPAC Name2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol
Molecular FormulaC19H17F6N7O
Molecular Weight473.4
XLogP3.5
Topological Polar Surface Area109
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Heavy Atom Count33
Formal Charge0
Complexity635
SMILES
CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
InChI
InChI=1S/C19H17F6N7O/c1-17(2,33)9-27-15-30-14(11-4-3-5-12(29-11)18(20,21)22)31-16(32-15)28-10-6-7-26-13(8-10)19(23,24)25/h3-8,33H,9H2,1-2H3,(H2,26,27,28,30,31,32)
InChIKey
DYLUUSLLRIQKOE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Enasidenib
CAS: 1446502-11-9
CID: 89683805
Formula: C19H17F6N7O
MW: 473.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight473.4
XLogP33.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Exact Mass473.13987716
Monoisotopic Mass473.13987716
Topological Polar Surface Area109 Ų
Heavy Atom Count33
Formal Charge0
Complexity635
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
A15808-50Enasidenib 50mg
A15808-10Enasidenib 10mg
A15808-5Enasidenib 5mg
A15808-500Enasidenib 500mg
A15808-200Enasidenib 200mg
A15808-100Enasidenib 100mg
A15808-10mM-DEnasidenib 10mM * 1mL in DMSO
A13047-25A-205804 25mg
A14328-25Sagopilone 25mg
A24249-25LXG6403 25mg

Alternative Products

CatalogName
MBS575336Enasidenib
MBS5773330Enasidenib mesylate
HY-18690SEnasidenib-d6
CS-EO-02982Enasidenib d6
HY-18690R-01Enasidenib (Standard)
HY-18690A-01Enasidenib (mesylate)
B7804-25AG-221 (Enasidenib)
206438Enasidenib (AG-221)

Popular Products