LGK-974 25mg

CAT: 0628-A12816-25Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0628-A12816-25Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1243244-14-5

Chemical Information

Wnt-974

LGK974 is a carboxamide, the structure of which is that of acetamide substituted on carbon by a 2',3-dimethyl-2,4'-bipyridin-5-yl group and on nitrogen by a 5-(pyrazin-2-yl)pyridin-2-yl group. It is a highly potent, selective and orally bioavailable Porcupine inhibitor (a Wnt signalling inhibitor). It has a role as a Wnt signalling inhibitor. It is a secondary carboxamide, a member of pyridines, a member of pyrazines and a member of bipyridines. It is functionally related to an acetamide.

CAS Number	1243244-14-5
PubChem CID	46926973
IUPAC Name	2-[5-methyl-6-(2-methyl-4-pyridinyl)-3-pyridinyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
Molecular Formula	C23H20N6O
Molecular Weight	396.4
XLogP	1.8
Topological Polar Surface Area	93.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Heavy Atom Count	30
Formal Charge	0
Complexity	560

SMILES

CC1=CC(=CN=C1C2=CC(=NC=C2)C)CC(=O)NC3=NC=C(C=C3)C4=NC=CN=C4

InChI

InChI=1S/C23H20N6O/c1-15-9-17(12-28-23(15)18-5-6-25-16(2)10-18)11-22(30)29-21-4-3-19(13-27-21)20-14-24-7-8-26-20/h3-10,12-14H,11H2,1-2H3,(H,27,29,30)

InChIKey

XXYGTCZJJLTAGH-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1243244-14-5

CID: 46926973

Formula: C23H20N6O

MW: 396.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	396.4
XLogP3	1.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	396.16985928
Monoisotopic Mass	396.16985928
Topological Polar Surface Area	93.6 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	560
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
A12816-5	LGK-974 5mg
A12816-1	LGK-974 1mg
A12816-100	LGK-974 100mg
A12816-2	LGK-974 2mg
A12816-50	LGK-974 50mg
A12816-10	LGK-974 10mg
A12816-10mM-D	LGK-974 10mM * 1mL in DMSO
A13047-25	A-205804 25mg
A14328-25	Sagopilone 25mg
A24570-25	DiI 25mg

Alternative Products

Catalog	Name
MBS385039-01	LGK-974
FL76327-01	LGK 974
366896-01	LGK974 (LGK-974, WNT-974, LGK 974, NVP-LGK974)
MBS3600986-01	WNT-974
T9901A-978-01	ERY-974
sc-222393	Tyrphostin AG 974

LGK-974 25mg

Chemical Information

Related Products

Alternative Products

Popular Products