GSK-923295 2mg

CAT: 0628-A11435-2Size: 2 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0628-A11435-2Size:2 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1088965-37-0

Chemical Information

Gsk-923295a

GSK-923295 is an imidazopyridine that is imidazo[1,2-a]pyridine substituted by 4-{(2S)-2-[3-chloro-4-(propan-2-yloxy)benzamido]-3-[(N,N-dimethylglycyl)amino]propyl}phenyl, and (1S)-1-hydroxyethyl groups at positions 2 and 8, respectively. It is an allosteric inhibitor of centromere-associated protein-E (CENP-E) kinesin motor ATPase activity (Ki = 3.2 nM and 1.6 nM for human and canine CENP-E motordomains, respectively). It has a role as a centromere protein E inhibitor, an antineoplastic agent and an antimitotic. It is a secondary carboxamide, a member of benzamides, an aromatic ether, a secondary alcohol, an imidazopyridine, a tertiary amino compound and a member of monochlorobenzenes.

CAS Number	1088965-37-0
PubChem CID	46898058
IUPAC Name	3-chloro-N-[(2S)-1-[[2-(dimethylamino)acetyl]amino]-3-[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-4-propan-2-yloxybenzamide
Molecular Formula	C32H38ClN5O4
Molecular Weight	592.1
XLogP	5
Topological Polar Surface Area	108
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Heavy Atom Count	42
Formal Charge	0
Complexity	870

SMILES

C[C@@H](C1=CC=CN2C1=NC(=C2)C3=CC=C(C=C3)C[C@@H](CNC(=O)CN(C)C)NC(=O)C4=CC(=C(C=C4)OC(C)C)Cl)O

InChI

InChI=1S/C32H38ClN5O4/c1-20(2)42-29-13-12-24(16-27(29)33)32(41)35-25(17-34-30(40)19-37(4)5)15-22-8-10-23(11-9-22)28-18-38-14-6-7-26(21(3)39)31(38)36-28/h6-14,16,18,20-21,25,39H,15,17,19H2,1-5H3,(H,34,40)(H,35,41)/t21-,25-/m0/s1

InChIKey

WHMXDBPHBVLYRC-OFVILXPXSA-N

Chemical Structure

2D Structure

CAS: 1088965-37-0

CID: 46898058

Formula: C32H38ClN5O4

MW: 592.1

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	592.1
XLogP3	5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Exact Mass	591.2612324
Monoisotopic Mass	591.2612324
Topological Polar Surface Area	108 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	870
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
A11435-5	GSK-923295 5mg
A11435-25	GSK-923295 25mg
A11435-50	GSK-923295 50mg
A11435-10	GSK-923295 10mg
A11435-1	GSK-923295 1mg
A11435-100	GSK-923295 100mg
A11435-10mM-D	GSK-923295 10mM * 1mL in DMSO
A19871-2	GSK-872 2mg
A16931-2	GSK-7975A 2mg
A14201-2	GSK-2193874 2mg

Alternative Products

Catalog	Name
A3450-10	GSK-923295
FG45994-01	GSK 923295
T25471-01	GSK-A
MBS131437	GSK163090 (GSK-163090; GSK 163090)
MBS131519	GSK369796 (GSK-369796, GSK 369796)
BA4485-5.1	GSK-25
B7751-100	GSK 2193874
A3445-5.1	GSK 525768A
BA6566-50	GSK-7975A

GSK-923295 2mg

Chemical Information

Related Products

Alternative Products

Popular Products