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Syringomycin E

CAT: 0804-HY-P3156Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-P3156Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
124888-22-8
UNSPSC Description
Syringomycin E is an antifungal cyclic lipodepsinonapeptide. Syringomycin E exhibits growth inhibition of Saccharomyces cerevisiae through interaction with the plasma membrane. Syringomycin E causes K+ efflux, Ca2+ influx, and changes in membrane potential, and is related to channel formation[1][2].
Target Antigen
Fungal
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/syringomycin-e.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@H](COC([C@](NC([C@](NC(/C(NC1=O)=C/C)=O)([H])[C@H](O)C(O)=O)=O)([H])[C@H](O)CCl)=O)NC(C[C@H](O)CCCCCCCCC)=O)=O)CO)=O)CCN)=O)CCN)=O)CCCNC(N)=N)N[C@H]1CC2=CC=CC=C2
Molecular Weight
1225.78
References & Citations
[1]Stock SD, et al. Syringomycin E inhibition of Saccharomyces cerevisiae: requirement for biosynthesis of sphingolipids with very-long-chain fatty acids and mannose- and phosphoinositol-containing head groups. Antimicrob Agents Chemother. 2000 May;44(5):1174-80. |[2]Efimova SS, et al. Alkaloids Modulate the Functioning of Ion Channels Produced by Antimicrobial Agents via an Influence on the Lipid Host. Front Cell Dev Biol. 2020 Jun 30;8:537.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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