11-Deoxy-16,16-dimethyl-PGE2

• UNSPSC Description:

  11-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress[1][2].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/11-deoxy-16-16-dimethyl-pge2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(CC1)=O)C/C=C\CCCC(O)=O

• Molecular Weight:

  364.52

• References & Citations:

  [1]R F Parrott, et al. Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig. Brain Res Bull. 1996;41(2):97-103. |[2]Kelly M Towndrow, et al. 11-Deoxy,16,16-dimethyl prostaglandin E2 induces specific proteins in association with its ability to protect against oxidative stress. Chem Res Toxicol. 2003 Mar;16(3):312-9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  53658-98-3