11-Deoxy-16,16-dimethyl-PGE2

11-Deoxy-16,16-dimethyl-PGE2

• CAS Number: 53658-98-3
• UNSPSC Description: 11-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress[1][2].
• Target Antigen: Prostaglandin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/11-deoxy-16-16-dimethyl-pge2.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(CC1)=O)C/C=C\CCCC(O)=O
• Molecular Weight: 364.52
• References & Citations: [1]R F Parrott, et al. Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig. Brain Res Bull. 1996;41(2):97-103. |[2]Kelly M Towndrow, et al. 11-Deoxy,16,16-dimethyl prostaglandin E2 induces specific proteins in association with its ability to protect against oxidative stress. Chem Res Toxicol. 2003 Mar;16(3):312-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported