Anti-Heme Oxygenase-2 Antibody

• Description:

  Rabbit Polyclonal Antibody specific to Heme oxygenase-2 (HO-2)

• Product Name Alternative:

  HO-2, EC 1.14.14.18

• Gene Name:

  Hmox2

• NCBI Gene ID:

  Hmox2

• UniProt:

  P23711

• Accession Number:

  NP_077363.1

• Cellular Locus:

  Microsome. Endoplasmic reticulum.

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Full-length native rat HO-2 purified from testes.

• Target Antigen:

  Heme oxygenase 2

• Target:

  Heme Oxygenase-2

• Clonality:

  Polyclonal

• Type:

  Antibody

• Applications:

  WB, IHC, IP

• Field of Research:

  Enzymes

• Purification Method:

  Purified by protein A affinity chromatography

• Concentration:

  Lot Specific

• Dilution:

  Dilute in PBS or medium that is identical to that used in the assay system.

• Format:

  Purified

• Form:

  Liquid

• Buffer:

  Phosphate Buffered Saline

• Function:

  Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

• Additionnal Information:

  Immunoblotting: use at 1ug/mL.Immunohistochemistsry: use at 1ug/mL.
  
  These are recommended concentrations.
  
  Endusers should determine optimal concentrations for their applications.

• Storage Conditions:

  Store at 2 - 8ºC. Do not Freeze.

• Specificity:

  Heme oxygenase-2

• Formulation:

  PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.

• Buffer pH:

  7.4

• CAS Number:

  9007-83-4