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Selaginellin

CAT: 0804-HY-N10083Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10083Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selaginellin is an inhibitor of Reactive Oxygen Species and an activator of SIRT1. Selaginellin protects endothelial cells against homocysteine-induced senescence by inhibitng reactive oxygen species and upregulating SIRT1 gene expression[1].
CAS Number
941269-84-7
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS) ; Sirtuin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/selaginellin.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C/C(C=C1)=C(C2=C(C(CO)=CC=C2C3=CC=C(O)C=C3)C#CC4=CC=C(C=C4)O)\C5=CC=C(C=C5)O
Molecular Formula
C34H24O5
Molecular Weight
512.55
References & Citations
[1]Wang CJ, et al. Effects of selaginellin on homocysteine-induced senescence in human umbilical vein endothelial cells. J Cardiovasc Pharmacol. 2010 Jun;55 (6) :560-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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