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αA-Conotoxin PIVA

CAT: 0804-HY-P5856Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-P5856Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
171439-59-1
UNSPSC Description
αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
[GCCGSY-{Hyp}-NAACH-{Hyp}-CSCKDR-{Hyp}-SYCGQ-NH2(Disulfidebridge:Cys2-Cys16,Cys3-Cys11,Cys14-Cys23)]
Molecular Weight
2648.89
References & Citations
[1]Teichert RW, et al. Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry. 2006 Jan 31;45(4):1304-12.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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