CL-197

CAT: 0804-HY-148191-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-148191-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CL-197 is an orally active and long-acting purine anti-HIV nucleoside reverse transcriptase inhibitor (NRTI) . CL-197 has potential effect on the research of viral, oncological and cerebrovascular diseases[1]. CL-197 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CAS Number

1030595-07-3

UNSPSC

12352005

Target

HIV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cl-197.html

Purity

99.32

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](F)[C@H](N2C=NC3=C(N)N=C(F)N=C32)O[C@@]1(CO)C#C

Molecular Formula

C12H11F2N5O3

Molecular Weight

311.24

References & Citations

[1]Hou J, et al. 4'-Ethynyl-2'-deoxy-2'-β-fluoro-2-fluoroadenosine: A Highly Potent and Orally Available Clinical Candidate for the Treatment of HIV-1 Infection. J Med Chem. 2023 Aug 24;66 (16) :11282-11293.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

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BA1980-1	CL-197
BA3715-10	SKLB-197
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SEA96421-01	PBDE 197
T25139	BC 197
MD304304-3	Cl-PEG3-Cl
T26134-01	RS 15385-197
T85664-01	Antibacterial agent 197
MBS3615923-01	RS 42358-197

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