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Cephalochromin

CAT: 0804-HY-124199Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124199Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI) . Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC50 of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL[1].
CAS Number
25908-26-3
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cephalochromin.html
Smiles
OC(C(C(C=C1O[C@@H](C2)C)=[C@@](C(O)=C3)[C@@](C(O)=C4)=C(C=C5O[C@@H](C6)C)C(C(O)=C5C6=O)=C4O)=C3O)=C1C2=O
Molecular Formula
C28H22O10
Molecular Weight
518.47
References & Citations
[1]Zheng CJ, et al., Cephalochromin, a FabI-directed antibacterial of microbial origin. Biochem Biophys Res Commun. 2007 Nov 3;362 (4) :1107-12.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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