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Anacardic Acid

CAT: 0804-HY-N2020-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2020-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC50s of ∼8.5 μM and ∼5 μM, respectively.
CAS Number
16611-84-0
Product Name Alternative
Hydroginkgolic acid; Ginkgolic Acid C15:0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Epigenetic Reader Domain; Histone Acetyltransferase
Type
Natural Products
Related Pathways
Anti-infection; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Anacardic_Acid.html
Purity
98.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=C(CCCCCCCCCCCCCCC)C=CC=C1O
Molecular Formula
C22H36O3
Molecular Weight
348.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Balasubramanyam K, et al. Small molecule modulators of histone acetyltransferase p300. J Biol Chem. 2003 May 23;278 (21) :19134-40. Epub 2003 Mar 6.|[2]Peng C, et al. Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice. Mol Biosyst. 2017 Mar 28;13 (4) :714-724.|[3]Muzaffar S, et al. Anacardic acid induces apoptosis-like cell death in the rice blast fungus Magnaporthe oryzae. Appl Microbiol Biotechnol. 2016 Jan;100 (1) :323-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CBP/p300; GCN5/PCAF

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