ML-228

CAT: 0026-B2633-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2633-5Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-228 is an activator of the Hypoxia Inducible Factor (HIF) signaling pathway, as demonstrated by HIF response element (HRE) reporter assay (EC50 = 1.2 µM), HIF-1α nuclear translocation assay (EC50 = 1.3 µM), and increased VEGF expression (EC50 = 1.6 µM). Its activity in the HRE assay is blocked by excess iron, suggesting that ML-228 can chelate iron. ML-228 also significantly inhibits ligand binding to several channels, receptors, and transporters, including ERG potassium channel, 5-HT2B and A3 adenosine receptors, and dopamine transporter.
Storage Conditions
-20ºC
Shelf Life
36 months

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255856-01ML 228
A15360-1ML 228 1mg
A15360-5ML 228 5mg
A15360-25ML 228 25mg
A15360-50ML 228 50mg
A15360-10ML 228 10mg
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