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D-Tyrosine-d4

CAT: 0804-HY-Y0444S1-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0444S1-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Tyrosine-d4 is the deuterium labeled D-Tyrosine. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[2][3].
CAS Number
944386-47-4
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Isotope-Labeled Compounds; Tyrosinase
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 1mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 0.1mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC([C@H](N)CC1=C([2H])C([2H])=C(C([2H])=C1[2H])O)=O
Molecular Formula
C9H7D4NO3
Molecular Weight
185.21
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Cong Yu, et al. Inhibition of Biofilm Formation by D-tyrosine: Effect of Bacterial Type and D-tyrosine Concentration. Water Res. 2016 Apr 1;92:173-9.|[3]Jisu Park, et al. D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity. Pigment Cell Melanoma Res. 2018 May;31 (3) :374-383.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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