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5,6-Dihydroxyindole

CAT: 0804-HY-W018025-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W018025-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens[1].
CAS Number
3131-52-0
UNSPSC
12352005
Hazard Statement
H302, H318, H411
Target
Bacterial; Endogenous Metabolite; Fungal; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-6-dihydroxyindole.html
Purity
99.77
Solubility
DMSO : 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Smiles
OC1=CC2=C(C=C1O)C=CN2
Molecular Formula
C8H7NO2
Molecular Weight
149.15
Precautions
H302, H318, H411
References & Citations
[1]Zhao P, et al. Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochem Mol Biol. 2011 Sep;41 (9) :645-52.|[2]Heiduschka P, et al. Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitroand in vivo. Toxicol Pathol. 2007 Dec;35 (7) :1030-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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