(E) -Cardamonin (Standard)

• Description:

  (E) -Cardamonin (Standard) is the analytical standard of (E) -Cardamonin. This product is intended for research and analytical applications. (E) -Cardamonin ((E) -Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.

• Product Name Alternative:

  (E) -Cardamomin (Standard) ; (E) -Alpinetin chalcone (Standard)

• UNSPSC:

  12352005

• Target:

  Apoptosis; Reference Standards; TRP Channel

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-cardamonin-standard.html

• Smiles:

  O=C (C1=C (OC) C=C (O) C=C1O) /C=C/C2=CC=CC=C2

• Molecular Formula:

  C16H14O4

• Molecular Weight:

  270.28

• References & Citations:

  [1]Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21 (9) . pii: E1145.|[2]Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  19309-14-9