(E)-Cardamonin (Standard)

• UNSPSC Description:

  (E)-Cardamonin (Standard) is the analytical standard of (E)-Cardamonin. This product is intended for research and analytical applications. (E)-Cardamonin ((E)-Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.

• Target Antigen:

  Apoptosis; TRP Channel

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis;Membrane Transporter/Ion Channel;Neuronal Signaling

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-cardamonin-standard.html

• Smiles:

  O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=CC=C2

• Molecular Weight:

  270.28

• References & Citations:

  [1]Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21(9). pii: E1145.|[2]Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.

• Shipping Conditions:

  Room temperature

• CAS Number:

  19309-14-9