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FA-Ala-Arg

CAT: 0804-HY-P4523Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P4523Size:1 Each
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Description
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO) . FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL) -treated cells, PRL regulates CPD mRNA levels in cells[1].
CAS Number
[76079-06-6]
UNSPSC
12352209
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/fa-ala-arg.html
Solubility
10 mM in DMSO
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC(/C=C/C1=CC=CO1)=O)=O
Molecular Formula
C16H23N5O5
Molecular Weight
365.38
References & Citations
[1]Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149 (10) :4821-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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