FA-Ala-Arg

• Description :

  FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO) . FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL) -treated cells, PRL regulates CPD mRNA levels in cells[1].

• UNSPSC :

  12352209

• Target :

  Endogenous Metabolite

• Type :

  Peptides

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/fa-ala-arg.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](C)NC(/C=C/C1=CC=CO1)=O)=O

• Molecular Formula :

  C16H23N5O5

• Molecular Weight :

  365.38

• References & Citations :

  [1]Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149 (10) :4821-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [76079-06-6]