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Opipramol (Standard)

CAT: 0804-HY-118901RSize: 1 EachDry Ice: NoHazardous: No
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Description
Opipramol (Standard) is the analytical standard of Opipramol. This product is intended for research and analytical applications. Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) . Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) [1][2].
CAS Number
315-72-0
Product Name Alternative
Ensidon (Standard) ; G-33040 (Standard)
UNSPSC
12352005
Target
Reference Standards; Sigma Receptor
Type
Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/opipramol-standard.html
Smiles
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1
Molecular Formula
C23H29N3O
Molecular Weight
363.50
References & Citations
[1]H J Möller, et al. Opipramol for the treatment of generalized anxiety disorder: a placebo-controlled trial including an alprazolam-treated group. J Clin Psychopharmacol. 2001 Feb;21 (1) :59-65. |[2]T S Rao, et al. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. 1990 Dec;29 (12) :1191-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Opipramol

2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.

CAS Number315-72-0
PubChem CID9417
IUPAC Name2-[4-(3-benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol
Molecular FormulaC23H29N3O
Molecular Weight363.5
XLogP3.6
Topological Polar Surface Area30
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count27
Formal Charge0
Complexity448
SMILES
C1CN(CCN1CCCN2C3=CC=CC=C3C=CC4=CC=CC=C42)CCO
InChI
InChI=1S/C23H29N3O/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26/h1-4,6-11,27H,5,12-19H2
InChIKey
YNZFUWZUGRBMHL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Opipramol
CAS: 315-72-0
CID: 9417
Formula: C23H29N3O
MW: 363.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight363.5
XLogP33.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass363.231062557
Monoisotopic Mass363.231062557
Topological Polar Surface Area30 Ų
Heavy Atom Count27
Formal Charge0
Complexity448
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes