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Opipramol

CAT: 0804-HY-118901-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-118901-01Size:5 mg
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Description
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) . Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) [1][2].
CAS Number
315-72-0
Product Name Alternative
Ensidon; G-33040
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/opipramol.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1
Molecular Formula
C23H29N3O
Molecular Weight
363.50
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]H J Möller, et al. Opipramol for the treatment of generalized anxiety disorder: a placebo-controlled trial including an alprazolam-treated group. J Clin Psychopharmacol. 2001 Feb;21 (1) :59-65. |[2]T S Rao, et al. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. 1990 Dec;29 (12) :1191-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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