NQO1 substrate
CAT:
804-HY-114315-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NQO1 substrate
- Product Name Alternative: AM152
- CAS Number: 2304503-05-5
- UNSPSC Description: NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1].
- Target Antigen: Quinone Reductase
- Type: Reference compound
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nqo1-substrate.html
- Purity: 98.02
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: N#CC1=C(C#N)N=C2C(C(C3=C2C=C(F)C(F)=C3)=O)=N1
- Molecular Weight: 268.18
- References & Citations: [1]Wu X, et al. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2018 Dec 27;61(24):11280-11297.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported