N-Butanoyl-DL-homoserine lactone

N-Butanoyl-DL-homoserine lactone

• Product Name Alternative: trans-PX-102
• CAS Number: 98426-48-3
• UNSPSC Description: N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1][2].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/n-butanoyl-dl-homoserine-lactone.html
• Purity: 98.0
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CCCC(NC1C(OCC1)=O)=O
• Molecular Weight: 171.196
• References & Citations: [1]Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19;14(2):e0212041.|[2]Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported