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GGT2 rabbit pAb

CAT: 0855-ES16189-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES16189-01Size:50 µL
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Background
GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]) .[supplied by OMIM, Oct 2008]
Description
GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008 [PubMed 18357469]). [supplied by OMIM, Oct 2008],
Product Name Alternative
Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]
UniProt
P36268
Swiss Prot
P36268
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human GGT2 AA range: 89-139
Target
GGT2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Cytoplasm, perinuclear region . Endoplasmic reticulum . Co-localizes with calnexin in the endoplasmic reticulum.
Other Product Names
Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]

UniProtKB · P36268

Inactive glutathione hydrolase 2

GGT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P36268
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GGT2P
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulum

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Domain

Signal

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