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Atecegatran (TFA)

CAT: 0804-HY-10275A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10275A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atecegatran TFA (AR-H067637 TFA) is an anticoagulant with selective direct thrombin inhibitory activity. Atecegatran TFA is commonly used to inhibit cardiovascular diseases. The biotransformation product of Atecegatran TFA, AR-H067637, is its active form and participates in the anticoagulation process[1].
CAS Number
433937-75-8
Product Name Alternative
AR-H067637 (TFA)
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/atecegatran-tfa.html
Smiles
OC(C(F)(F)F)=O.O[C@H](C1=CC(OC(F)F)=CC(Cl)=C1)C(N2[C@@H](CC2)C(NCC3=CC=C(C=C3)C(N)=N)=O)=O
Molecular Formula
C23H22ClF5N4O6
Molecular Weight
580.89
References & Citations
[1]Deinum J, et al. Biochemical and pharmacological effects of the direct thrombin inhibitor AR-H067637. Thromb Haemost. 2009 Jun;101 (6) :1051-9.|[2]Deinum J, et al. Biochemical and pharmacological effects of the direct thrombin inhibitor AR-H067637. Thromb Haemost. 2009 Jun;101 (6) :1051-9.|[3]Effects of AZD0837, a novel direct thrombin inhibitor, on the electrophysiological properties of the human heart: a randomized, double-blind, parallel-group, placebo-controlled study
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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