PUMA BH3

CAT: 0804-HY-P1562-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P1562-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.
UNSPSC
12352209
Target
Bcl-2 Family
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PUMA_BH3.html
Purity
98.24
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C100H162N34O32S
Molecular Weight
2384.63
References & Citations
[1]Lopez A, et al. Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer. Nat Commun. 2022 Mar 7;13 (1) :1199.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Bak

Related Products

CatalogName
HY-P5328-01Noxa A BH3
HY-P5341Bik BH3
HY-P2343-01BH3 (hydrochloride)
HY-P1733BMf-BH3
HY-P5342-01Hrk BH3
HY-P0300Bak BH3
HY-P1527-01Bim BH3
HY-P5327R8 Bid BH3
HY-P5324Bad BH3 (mouse)
HY-P10614Bid BH3 peptide

Alternative Products

CatalogName
1288PUMA Adenovirus (Ad-PUMA)
E8ET1602-24PUMA
1289PUMA (DBH3) Adenovirus (Ad-PUMA (DBH3) )
MBS9435425-01PUMA Antibody
E8ER1904-14BBC3/PUMA
MBS152664-01PUMA Peptide
MBS435293-01Puma mAb

Popular Products