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Salcaprozate (sodium)

CAT: 0804-HY-114299-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114299-01Size:250 mg
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Description
Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation[1][2].
CAS Number
203787-91-1
Product Name Alternative
SNAC
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/salcaprozate-sodium.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O[Na])CCCCCCCNC(C1=CC=CC=C1O)=O
Molecular Formula
C15H20NNaO4
Molecular Weight
301.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Riley MGI, et, al. Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats. Int J Toxicol. Jul-Aug 2009; 28 (4) :278-93.|[2]Twarog C, et, al. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C 10) . Pharmaceutics. 2019 Feb 13; 11 (2) :78.|[3]Li Y, et, al. Impact of Sodium N-[8- (2-Hydroxybenzoyl) amino]-caprylate on Intestinal Permeability for Notoginsenoside R1 and Salvianolic Acids in Caco-2 Cells Transport and Rat Pharmacokinetics. Molecules. 2018 Nov 16; 23 (11) :2990.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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