Heptadecanoic acid

• Description:

  Heptadecanoic acid is an odd-chain saturated fatty acid (OCS-FA) with oral activity. Heptadecanoic acid can inhibit cell proliferation and induce Apoptosis. Heptadecanoic acid has antitumor activity. Heptadecanoic acid is associated with a number of diseases, including coronary heart disease, pre-diabetes and type 2 diabetes, and multiple sclerosis[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H315, H319

• Target:

  Akt; Apoptosis; PI3K

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; PI3K/Akt/mTOR

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Cancer; Metabolic Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/heptadecanoic-acid.html

• Purity:

  99.90

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles:

  O=C(CCCCCCCCCCCCCCCC)O

• Molecular Formula:

  C17H34O2

• Molecular Weight:

  270.45

• Precautions:

  H315, H319

• References & Citations:

  [1]Changzhi Xu, et al. Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistancey. Oncol Rep. 2019 Jun;41 (6) :3499-3507.|[2]Zhao L, et al. Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats. Microbiome. 2018 Jun 14;6 (1) :107.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [506-12-7]