12(S)​-​Hydroxy-​16-​heptadecynoic acid

• Product Name Alternative:

  (12S)-12-Hydroxy-15-hexadecynoic acid

• UNSPSC Description:

  12(S)-Hydroxy-16-heptadecynoic acid ((12S)-12-Hydroxy-15-hexadecynoic acid) is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase. It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 μM.

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/12-s-hydroxy-16-heptadecynoic-acid.html

• Smiles:

  C#CCCC[C@@H](O)CCCCCCCCCCC(O)=O

• Molecular Weight:

  282.42

• References & Citations:

  [1]Burger, et al. Mechanism-based inhibitors of prostaglandin w -hydrolase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J. Med. Chem. 36, 1418-1424 (1993).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  148019-74-3