Linoleic acid-d4

Linoleic acid-d4

• CAS Number: 79050-23-0
• UNSPSC Description: Linoleic Acid-d4 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Metabolic Disease; Cardiovascular Disease
• Purity: 98.10
• Solubility: 10 mM in DMSO
• Smiles: CCCCC/C([2H])=C(C/C([2H])=C(CCCCCCCC(O)=O)/[2H])/[2H]
• Molecular Weight: 284.47
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4(3): 311–312.|[3]Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8(5):5044-52.
• Shipping Conditions: Blue Ice
• Storage Conditions: Solution, -20°C, 2 years
• Clinical Information: No Development Reported