Products for Research Use Only
RegisterLogin

Danazol (Standard)

CAT: 0804-HY-B1029R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1029R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Danazol standard inhibits the proliferation of cancer cell MDA-MB-231 and MCF-7 with IC50 of 65 µg/mL and 31 µg/mL. Danazol arrests the cell cycle at G1 phase, induces apoptosis in MDA-MB-231 through PKCα signaling pathway[1].
CAS Number
17230-88-5
UNSPSC
12352005
Target
Apoptosis; PKC; Reference Standards; Tyrosinase
Type
Reference Standards
Related Pathways
Apoptosis; Epigenetics; Metabolic Enzyme/Protease; Others; TGF-beta/Smad
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/danazol-standard.html
Smiles
C#C[C@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC5=C(C=NO5)C[C@]4(C)[C@@]3([H])CC[C@@]21C
Molecular Formula
C22H27NO2
Molecular Weight
337.46
References & Citations
[1]Thomas GW, et al., Effects of danazol on endothelial cell function and angiogenesis. Fertil Steril. 2007 Oct;88 (4 Suppl) :1065-70.|[2]Chang TS, Lin JJ. Inhibitory effect of danazol on melanogenesis in mouse B16 melanoma cells. Arch Pharm Res. 2010 Dec;33 (12) :1959-65. |[3]Deka SJ, et al., Danazol has potential to cause PKC translocation, cell cycle dysregulation, and apoptosis in breast cancer cells. Chem Biol Drug Des. 2017 Jun;89 (6) :953-963.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched

Related Products

CatalogName
HY-B1029-01Danazol
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)
HY-N3373RLoganetin (Standard)

Alternative Products

CatalogName
TRC-D145000-1GDanazol
D145002Danazol-13C3
AR-D06290-01Danazol-d3
271208-01Danazol discontinued
RM-D100005-01Danazol Impurity 5
RM-D100004-01Danazol Impurity 4
RM-D100003-01Danazol Impurity 3
AR-D08092-01Danazol Nitrile Impurity
RM-D100002-01Danazol Impurity 2
AR-D08090-01Danazol Open Ring Enol Impurity

Popular Products