Butabindide (oxalate)

Butabindide (oxalate)

• CAS Number: 185213-03-0
• UNSPSC Description: Butabindide (UCL-1397) oxalate is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation[1][2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/butabindide-oxalate.html
• Purity: 98.98
• Solubility: H2O : 39 mg/mL (ultrasonic;warming)
• Smiles: O=C([C@H]1N(C([C@@H](N)CC)=O)C2=C(C=CC=C2)C1)NCCCC.O=C(O)C(O)=O
• Molecular Weight: 393.43
• References & Citations: [1]Ganellin CR, et, al. Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors. J Med Chem. 2005 Nov 17;48(23):7333-42.|[2]Rose C, et, al. Characterization and inhibition of a cholecystokinin-inactivating serine peptidase. Nature. 1996 Apr 4;380(6573):403-9.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported