Products for Research Use Only
RegisterLogin

Integrin αIIb rabbit pAb

CAT: 0855-ES20280-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES20280-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Description
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
UniProt
P08514
Swiss Prot
P08514
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human Integrin αIIb AA range: 1-80
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
Integrin alpha-IIb (GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]
Gene ID (Human)
3674

Related Products

CatalogName
ES2629-01Integrin αV rabbit pAb
ES2628-01Integrin α3 rabbit pAb
ES4319-01Integrin α5 rabbit pAb
ES8646-01Integrin α1 rabbit pAb
ES5949-01Integrin β1 rabbit pAb
ES4320-01Integrin α6 rabbit pAb
ES4308-01Integrin αL rabbit pAb
ES4190-01Integrin αD rabbit pAb
ES4191-01Integrin β2 rabbit pAb
ES5952-01Integrin β2 rabbit pAb

Alternative Products

CatalogName
E44H16391Integrin αIIb rabbit pAb
GTR18603189-01Integrin alpha IIb Rabbit pAb
E2R22855Integrin alpha IIb Rabbit mAb
E10G20946Integrin alpha IIb Rabbit Monoclonal Antibody
ARM2809-01Integrin alpha IIb Recombinant Rabbit mAb
APRab00178-01Integrin alpha IIb Rabbit Polyclonal Antibody
WP17696-01U-Blot® Integrin αIIb rabbit pAb
GTR18711161Integrin alpha IIb Rabbit mAb Antibody
E2381775CD41/Integrin alpha IIb Rabbit pAb
E28M1215Integrin alpha IIb (10J13) Rabbit Monoclonal Antibody

Popular Products