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Quadrol

CAT: 0804-HY-B2149-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2149-01Size:500 mg
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Description
Quadrol is an immunostimulant that has been considered as a potentially useful active molecule for accelerating wound healing. Quadrol can form a complex with Ca2+, mediate the entry of Ca2+ into macrophages, and stimulate macrophage activation.
CAS Number
102-60-3
Product Name Alternative
N, N, N′, N′-Tetrakis (2-hydroxypropyl) ethylenediamine; EDTP
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Quadrol.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
CC(O)CN(CC(O)C)CCN(CC(O)C)CC(O)C
Molecular Formula
C14H32N2O4
Molecular Weight
292.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Bhide MV, et al. In vitro stimulation of macrophages by quadrol [N, N, N', N'-tetrakis (2-hydroxypropyl) ethylenediamine]. J Immunopharmacol. 1985;7 (3) :303-12.|[2]Bhide MV, et al. Promotion of wound collagen formation in normal and diabetic mice by quadrol. Immunopharmacol Immunotoxicol. 1988;10 (4) :513-22.|[3]Bhide MV, et al. Investigation into the mechanism of stimulation of macrophages by Quadrol. Immunopharmacol Immunotoxicol. 1987;9 (1) :129-41.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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