Fosfomycin (tromethamine)
CAT:
804-HY-B0609-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Fosfomycin (tromethamine)
- CAS Number: 78964-85-9
- UNSPSC Description: Fosfomycin (MK-0955) tromethamine is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin tromethamine shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2].
- Target Antigen: Antibiotic; Bacterial
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-immunoregulation
- Field of Research: Infection; Cancer
- Assay Protocol: https://www.medchemexpress.com/fosfomycin-tromethamine.html
- Purity: 99.69
- Solubility: H2O : 250 mg/mL (ultrasonic)
- Smiles: C[C@@H]1O[C@@H]1P(O)(O)=O.OCC(CO)(N)CO
- Molecular Weight: 259.19
- References & Citations: [1]Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31;6(4). pii: E24.|[2]Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47.|[3]Inouye S, et al. Protective effect of fosfomycin on the experimental nephrotoxicity induced by dibekacin. J Pharmacobiodyn. 1982 Sep. 5(9):659-69.|[4]Inouye S, et al. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec. 5(12):941-50.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: Launched