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NSUN5 Rabbit Polyclonal Antibody

CAT: 0992-HA500544Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500544Size:100 µL
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Description
Putative methyltransferase NSUN5 is an enzyme that in humans is encoded by the NSUN5 gene. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development (By similarity). This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
CAS Number
9007-83-4
Product Name Alternative
FLJ10267 antibody MGC986 antibody NOL1 antibody NOL1-related protein antibody NOL1/NOP2/Sun domain family member 5 antibody NOL1R antibody NOP2/Sun domain family, member 5 antibody NOP2/Sun domain family, member 5A antibody NSUN5 antibody NSUN5_HUMAN antibody p120 antibody Putative methyltransferase NSUN5 antibody WBSCR20 antibody WBSCR20A antibody Williams Beuren syndrome chromosome region 20A antibody Williams-Beuren syndrome chromosomal region 20A protein antibody Williams-Beuren syndrome critical region protein 20 copy A antibody
Abbreviation
NSUN5, NSUN5A, WBSCR20, WBSCR20A
Swiss Prot
Q96P11 Human, Q8K4F6 Mouse,
Cellular Locus
Nucleus, nucleolus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human NSUN5 aa 51-100 / 429.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, A549 cell lysate, Caco-2 cell lysate, K-562 cell lysate, A431 cell lysate, L-929 cell lysate, MEF cell lysate, PC-12 cell lysate, human kidney tissue lysate, mouse kidney tissue lysate, mouse heart tissue lysate, mouse spleen tissue lysate, rat kidney tissue lysate, rat spleen tissue lysate, human skeletal muscle tissue, human placenta tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Concentration
2 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:500-1:2,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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