Products for Research Use Only
RegisterLogin

Lithospermic acid

CAT: 0804-HY-N0823-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0823-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lithospermic acid ((+) -Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4) -induced acute liver damage in vitro and in vivo[1].
CAS Number
28831-65-4
Product Name Alternative
(+) -Lithospermic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Apoptosis; Keap1-Nrf2; NO Synthase; Xanthine Oxidase
Type
Natural Products
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lithospermic-acid.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 66.67 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC4=CC=C(O)C(O)=C4)=O)=C13)O
Molecular Formula
C27H22O12
Molecular Weight
538.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Chan KW, et al. Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivo. Oncol Rep. 2015 Aug;34 (2) :673-80.|[2]Zhang M, et al., Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα) . Front Pharmacol. 2021 Nov 26;12:794982.|[3]Liu X, et al., Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats. Chem Biol Interact. 2008 Nov 25;176 (2-3) :137-42.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-W517110-01Deltamethric acid
HY-W342979-01Petroselaidic acid
HY-W004260-01Arachidic acid
HY-N0787-01Cryptochlorogenic acid
HY-N1984-01Artemisic acid

Alternative Products

CatalogName
MBS3840506-01lithospermic acid
A14660-500Lithospermic acid 500mg
A14660-25Lithospermic acid 25mg
A14660-100Lithospermic acid 100mg
A14660-50Lithospermic acid 50mg
A14660-10Lithospermic acid 10mg
A14660-5Lithospermic acid 5mg
A14660-1Lithospermic acid 1mg
GTR19158512-01Lithospermic acid B

Popular Products