β-Endorphin, rat

• Description :

  β-Endorphin, rat (β-Lipotropin 61-91), a neuropeptide, is involved in cardiovascular regulation. β-Endorphin, rat induces marked, prolonged muscular rigidity and immobility similar to a catatonic state in rats[1][2].

• Product Name Alternative :

  β-Lipotropin 61-91

• UNSPSC :

  12352209

• Target :

  Opioid Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/β-endorphin-rat-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)=O)=O)CCSC)=O)[C@@H](C)O)=O)CO)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCC(N)=O)=O)[C@@H](C)O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)CCCCN)=O)CCCCN)=O)=O)C)=O)CC(N)=O)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)C(C)C)=O)CC(C)C)=O)CCC3

• Molecular Formula :

  C155H250N42O44S

• Molecular Weight :

  3437.96

• References & Citations :

  [1]Bloom F, et al. Endorphins: profound behavioral effects in rats suggest new etiological factors in mental illness. Science. 1976 Nov 5;194 (4265) :630-2.|[2]Hill C, et al. The effects of beta-endorphin (beta-END) on cardiovascular and behavioral dynamics in conscious rats. Brain Res Bull. 2002 Oct 15;59 (1) :29-34.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [59887-17-1]