Hexylresorcinol

Hexylresorcinol

• CAS Number: 136-77-6
• UNSPSC Description: Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage[1][2][3][4][5].
• Target Antigen: Apoptosis; Bacterial; Endogenous Metabolite; Glycosidase; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Apoptosis;Metabolic Enzyme/Protease
• Field of Research: Cancer; Infection; Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/Hexylresorcinol.html
• Purity: 99.98
• Solubility: DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
• Smiles: OC1=CC=C(CCCCCC)C(O)=C1
• Molecular Weight: 194.274
• References & Citations: [1]Y. A. Nikolaev, et al. The use of 4-Hexylresorcinol as antibiotic adjuvant. PLoS One. 2020; 15(9): e0239147.|[2]Seong-Gon Kim, et al. 4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers. Oncol Rep. 2013 May;29(5):1835-40.|[3]Shuang Song, et al. Inhibitory potential of 4-hexylresorcinol against α-glucosidase and non-enzymatic glycation: Activity and mechanism. J Biosci Bioeng. 2020 Nov 12;S1389-1723(20)30400-X.|[4]Gow-Chin Yen, et al. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocyte. Free Radic Res. 2003 May;37(5):509-14.|[5]Min-Keun Kim, et al. 4-Hexylresorcinol induced angiogenesis potential in human endothelial cells. Maxillofac Plast Reconstr Surg. 2020 Dec; 42(1): 23.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched