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Hexylresorcinol

CAT: 0804-HY-B0986-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0986-01Size:500 mg
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Description
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage[1][2][3][4][5].
CAS Number
136-77-6
Product Name Alternative
4-Hexylresorcinol
UNSPSC
12352005
Hazard Statement
H302, H319, H411
Target
Apoptosis; Bacterial; Endogenous Metabolite; Glycosidase; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Hexylresorcinol.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCCCCC)C(O)=C1
Molecular Formula
C12H18O2
Molecular Weight
194.27
Precautions
H302, H319, H411
References & Citations
[1]Y. A. Nikolaev, et al. The use of 4-Hexylresorcinol as antibiotic adjuvant. PLoS One. 2020; 15 (9) : e0239147.|[2]Seong-Gon Kim, et al. 4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers. Oncol Rep. 2013 May;29 (5) :1835-40.|[3]Shuang Song, et al. Inhibitory potential of 4-hexylresorcinol against α-glucosidase and non-enzymatic glycation: Activity and mechanism. J Biosci Bioeng. 2020 Nov 12; S1389-1723 (20) 30400-X.|[4]Gow-Chin Yen, et al. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocyte. Free Radic Res. 2003 May;37 (5) :509-14.|[5]Min-Keun Kim, et al. 4-Hexylresorcinol induced angiogenesis potential in human endothelial cells. Maxillofac Plast Reconstr Surg. 2020 Dec; 42 (1) : 23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Human Endogenous Metabolite