Hexylresorcinol

• Description:

  Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage[1][2][3][4][5].

• Product Name Alternative:

  4-Hexylresorcinol

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H319, H411

• Target:

  Apoptosis; Bacterial; Endogenous Metabolite; Glycosidase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Apoptosis; Metabolic Enzyme/Protease

• Field of Research:

  Cancer; Infection; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Hexylresorcinol.html

• Concentration:

  10mM

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

• Smiles:

  OC1=CC=C(CCCCCC)C(O)=C1

• Molecular Formula:

  C12H18O2

• Molecular Weight:

  194.27

• Precautions:

  H302, H319, H411

• References & Citations:

  [1]Y. A. Nikolaev, et al. The use of 4-Hexylresorcinol as antibiotic adjuvant. PLoS One. 2020; 15 (9) : e0239147.|[2]Seong-Gon Kim, et al. 4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers. Oncol Rep. 2013 May;29 (5) :1835-40.|[3]Shuang Song, et al. Inhibitory potential of 4-hexylresorcinol against α-glucosidase and non-enzymatic glycation: Activity and mechanism. J Biosci Bioeng. 2020 Nov 12; S1389-1723 (20) 30400-X.|[4]Gow-Chin Yen, et al. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocyte. Free Radic Res. 2003 May;37 (5) :509-14.|[5]Min-Keun Kim, et al. 4-Hexylresorcinol induced angiogenesis potential in human endothelial cells. Maxillofac Plast Reconstr Surg. 2020 Dec; 42 (1) : 23.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [136-77-6]