(D-Met2,Pro5)-Enkephalinamide

(D-Met2,Pro5)-Enkephalinamide

• CAS Number: 63307-63-1
• UNSPSC Description: (D-Met2,Pro5)-Enkephalinamide is a highly potent opiate agonist, and shows antinociceptive activity[1][2][3].
• Target Antigen: Opioid Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/d-met2-pro5-enkephalinamide.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@H](CCSC)C(NCC(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N
• Molecular Weight: 612.74
• References & Citations: [1]Decsi L, et al. Effect of (D-Met2, Pro5)enkephalinamide, a highly potent opiate agonist, on the drinking behaviour of rats. Neuropharmacology. 1985 Jan;24(1):5-8.|[2]Nagy G, et al. (D-Met2,Pro5) enkephalinamide causes a decrease in plasma prolactin levels of lactating rats continuously suckled and an increase in those deprived of their litter. Regul Pept. 1984 Jul;8(4):321-6.|[3]Wollemann M, et al. Effect of Met-enkephalin and (D-Met2,Pro5)-enkephalinamide on the adenylate cyclase activity of rat brain. Neurochem Res. 1979 Oct;4(5):627-31.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported