(D-Met2,Pro5)-Enkephalinamide

• UNSPSC Description:

  (D-Met2,Pro5)-Enkephalinamide is a highly potent opiate agonist, and shows antinociceptive activity[1][2][3].

• Target Antigen:

  Opioid Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/d-met2-pro5-enkephalinamide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@H](CCSC)C(NCC(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N)=O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N

• Molecular Weight:

  612.74

• References & Citations:

  [1]Decsi L, et al. Effect of (D-Met2, Pro5)enkephalinamide, a highly potent opiate agonist, on the drinking behaviour of rats. Neuropharmacology. 1985 Jan;24(1):5-8.|[2]Nagy G, et al. (D-Met2,Pro5) enkephalinamide causes a decrease in plasma prolactin levels of lactating rats continuously suckled and an increase in those deprived of their litter. Regul Pept. 1984 Jul;8(4):321-6.|[3]Wollemann M, et al. Effect of Met-enkephalin and (D-Met2,Pro5)-enkephalinamide on the adenylate cyclase activity of rat brain. Neurochem Res. 1979 Oct;4(5):627-31.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  63307-63-1